A 60-year-old woman developed a periorbital lipogranuloma after endonasal s
urgery on her paranasal sinuses. The granulomatous inflammation was caused
by nonabsorbable lipids introduced by the postoperative nasal tamponade whi
ch was soaked in antibiotic ointment. These lipids were transported into th
e periorbital tissue by the postoperative hemorrhage. Since the course of t
he inflammatory process is chronic,surgical removal is the best treatment.