Catalytic hydrogenation and deuteration of phospholipid model membranes with a water-soluble chlorotris(1,3,5-triaza-7-phosphaadamantane)rhodium(I) complex catalyst

Authors
Nadasdi, L Joo, F
Citation
L. Nadasdi et F. Joo, Catalytic hydrogenation and deuteration of phospholipid model membranes with a water-soluble chlorotris(1,3,5-triaza-7-phosphaadamantane)rhodium(I) complex catalyst, INORG CHIM, 293(2), 1999, pp. 218-222
Citations number
22
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
INORGANICA CHIMICA ACTA
ISSN journal
00201693 → ACNP
Volume
293
Issue
2
Year of publication
1999
Pages
218 - 222
Database
ISI
SICI code
0020-1693(19991015)293:2<218:CHADOP>2.0.ZU;2-3
Abstract
The water-soluble chlorotris(1,3,5-triaza-7-phosphaadamantane)rhodium(I) [R hCl(PTA)(3)], was successfully employed for hydrogenation of phospholipid l iposomes as model membranes in aqueous media under mild conditions. The hig hest conversion was achieved at pH 4.70. Formation of asymmetrically dideut erated lipids, together with isomerization and kinetic results revealed the important role of reversible formation of an alkyl-rhodium intermediate in the mechanism. (C) 1999 Elsevier Science S.A. All rights reserved.