Na. Semenova et al., Disturbed energy metabolism in rat brain after extreme influences: a new method to evaluate energy state of the brain, IAN BIOL, (4), 1999, pp. 444-452
We propose a new method to evaluate energy state of the brain based on vita
l assay for phosphate metabolites and intracellular pH in the brain. A prop
osed Z-index describes a set of correlations between phosphates involved in
brain energy metabolism assayed in vivo by magnetic resonance spectroscopy
on P-31 nuclei. We tried to use Z-index as a quantitative test for disturb
ed energy metabolism. Potentialities of Z-index for evaluating rat brain en
ergy state after extreme influences (X-irradiation and postoperative shock
of the brain cortex) have been demonstrated.