Stereoselective synthesis of flavonoids. Part 8. Free phenolic flavan-3-oldiastereoisomers

Authors
Reinier,"Nel, JJ van Rensburg, H van Heerden, PS Ferreira, D
Citation
Jj. Reinier,"nel et al., Stereoselective synthesis of flavonoids. Part 8. Free phenolic flavan-3-oldiastereoisomers, J CHEM R-S, (10), 1999, pp. 606-607A
Citations number
18
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF CHEMICAL RESEARCH-S
ISSN journal
03082342 → ACNP
Issue
10
Year of publication
1999
Pages
606 - 607A
Database
ISI
SICI code
0308-2342(199910):10<606:SSOFP8>2.0.ZU;2-X
Abstract
Asymmetric dihydroxylation of a series of poly-O-methoxymethyl-1,3-diarylpr openes with AD-mix-alpha or AD-mix-beta and subsequent acid-catalyzed cycli zation of the intermediate syn-diols permits the first synthetic access to all four diastereoisomers of free phenolic flavan-3-ols in high enantiomeri c excess and yield.