A phytochemical investigation of Onopordum illyricum afforded, in addition
to several known compounds, two new eudesmane sesquiterpenes (1 and 2), two
new elemane sesquiterpenes (3 and 4), and one new neolignan derivative (5)
. The structure elucidation of all compounds was based on their H-1 and C-1
3 NMR spectral data, including those derived from ID TOCSY, 2D NMR, COSY-DQ
F, HSQC, and HMBC experiments, as well as extensive 1D ROESY studies.