EFFICACY OF INTRACYTOPLASMIC SPERM INJECTION (ICSI) TREATMENT IN THE IMMUNOLOGICAL INFERTILE PATIENTS

PROBLEM: To evaluate the efficacy of intracytoplasmic sperm injection (ICSI) treatment in the immunological infertile patients. METHODS: The subjects were 60 cycles of 44 immunological infertile patients and th ese clinical data were analysed, retrospectively. They were classified into female and male immunological infertility group and were treated with conventional IVF, ICSI, and half-ICSI. RESULTS: The fertilizatio n rate of ICSI (60.3%) and half-ICSI (60.7%) cycles were significantly (P<0.01) higher than conventional IVF (42.6%) cycles. In the male imm unological infertility group, fertilization rate was significantly (P< 0.01) higher in ICSI (60.7%) and half-ICSI (66.7%) cycles than in conv entional IVF (27.4%) cycles and clinical pregnancy rate was higher in ICSI (54.5%) and half ICSI (33.3%) than in conventional IVF (25.0%) cy cles. CONCLUSIONS: We suggest that ICSI treatment is highly effective method to improve fertilization and pregnancy rate in IVF-ET program o f male immunological infertility.