During dissection of a cadaver at the Ohio College of Pediatric Medicine, t
he authors encountered the os subfibulare. The os subfibulare was encased w
ithin the peroneus longus and peroneus brevis tendons and initially appeare
d as though it may have articulated with the left lateral malleolus distall
y and posteriorly. The ossicle was not associated with any capsular or liga
mentous structures. These findings suggest that the os subfibulare is a tru
e sesamoid bone. A review of the literature is presented and the clinical s
ignificance of these findings is discussed.