Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine

Authors
Stoeber, K Halsall, I Freeman, A Swinn, R Doble, A Morris, L Coleman, N Bullock, N Laskey, RA Hales, CN Williams, GH
Citation
K. Stoeber et al., Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine, LANCET, 354(9189), 1999, pp. 1524-1525
Citations number
6
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
LANCET
ISSN journal
01406736 → ACNP
Volume
354
Issue
9189
Year of publication
1999
Pages
1524 - 1525
Database
ISI
SICI code
0140-6736(19991030)354:9189<1524:IFUCTD>2.0.ZU;2-U
Abstract
Cancer-screening tests for internal organs are severely constrained by low specificity or sensitivity, cost, and morbidity. We report a non-invasive i mmunofluorometric assay for detection of urothelial cancers based on ectopi c expression of the DNA replication protein Mcm5.