Lipoprotein(a) and the estimation of low-density cholesterol by the formula of Friedewald: a new problem for an old equation

Authors
Hernandez, C Chacon, P Garcia-Pascual, L Rossello, J Simo, R
Citation
C. Hernandez et al., Lipoprotein(a) and the estimation of low-density cholesterol by the formula of Friedewald: a new problem for an old equation, MED CLIN, 113(8), 1999, pp. 290-291
Citations number
11
Categorie Soggetti
General & Internal Medicine
Journal title
MEDICINA CLINICA
ISSN journal
00257753 → ACNP
Volume
113
Issue
8
Year of publication
1999
Pages
290 - 291
Database
ISI
SICI code
0025-7753(19990918)113:8<290:LATEOL>2.0.ZU;2-Q
Abstract
BACKGROUND: To evaluate the influence of lipoprotein(a) [Lp(a)] concentrati on an the LDL-cholesterol calculated by the Friedewald formula. MATERIAL AND METHODS: Lp(a) was determined to a worker population of 947 su bject in order to perform a correction of LDL-cholesterol obtained by the F riedewald formula. RESULTS: In subjects in whom Lp(a) was > 30 mg/dl (12.9%) LDL cholesterol l evels were overestimated 10 mg/dl at least. CONCLUSION: Lp(a) should be considered in order to reduce Friedewald's form ula error on the estimation of LDL-cholesterol.