Multimodal treatment concepts in gastrointestinal tumors

A large variety of adjuvant and neoadjuvant treatment concepts were develop ed during the recent years to improve the results of gastrointestinal tumor s. Three exist generally accepted guidelines for adjuvant treatment of colo n and rectal cancer, while for the tumors of the upper gastrointestinal tra ct convincing results of randomized studies are still missing. Therefore on going and future studies have to find out, which patients could have a bene fit from multimodal therapy.