Molecular-biological investigations of the multicenter stage-III study (SIC-study)

Authors
Zimmermann, T Albrecht, S von Gagern, G
Citation
T. Zimmermann et al., Molecular-biological investigations of the multicenter stage-III study (SIC-study), MED KLIN, 94, 1999, pp. 58-61
Citations number
7
Categorie Soggetti
General & Internal Medicine
Journal title
MEDIZINISCHE KLINIK
ISSN journal
07235003 → ACNP
Volume
94
Year of publication
1999
Supplement
3
Pages
58 - 61
Database
ISI
SICI code
0723-5003(19991015)94:<58:MIOTMS>2.0.ZU;2-T
Abstract
Transcription factors adjust the up- and downregulation of inflammatory gen es. Within the bounds of the the SIC-study (Selenium in Intensive Care) the authors will investigate the role of transcription factors NF-kappa B and AP-1 in S.I.R.S/septic patients. The goal of these investigations is the corroboration of therapy of septic patients with sodium selenite at the molecularbiological level.