Hemolytic-uremic syndrome with involvement of basal ganglia and cerebellum

Hemolytic-uremic syndrome is a microangiopathy often associated with neurol ogic symptoms. Several patients with persistent lessons in cerebrum and bas al ganglia have been reported, We present two children with bilateral basal ganglia and additional unilateral cerebellar lesions in magnetic resonance imaging. These resolved completely in one child. in the other child there were still residuals after 11 weeks. The neurologic symptoms of both improv ed after several therapeutic plasma exchanges and disappeared after months.