Synthetic utility of organometallic reagents derived from group IV metal tetrachlorides and CH3Li. A direct synthesis of 2-(2-keto-1-alkylidene)tetrahydropyrroles from 4-alkynylamines and acyl cyanides

Authors
Duncan, D Livinghouse, T
Citation
D. Duncan et T. Livinghouse, Synthetic utility of organometallic reagents derived from group IV metal tetrachlorides and CH3Li. A direct synthesis of 2-(2-keto-1-alkylidene)tetrahydropyrroles from 4-alkynylamines and acyl cyanides, ORGANOMETAL, 18(21), 1999, pp. 4421-4428
Citations number
15
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANOMETALLICS
ISSN journal
02767333 → ACNP
Volume
18
Issue
21
Year of publication
1999
Pages
4421 - 4428
Database
ISI
SICI code
0276-7333(19991011)18:21<4421:SUOORD>2.0.ZU;2-F
Abstract
The non-Cp-bearing titanium alkyls (CH3)(2)TiCl2. L-2 (1a) and (CH3)(2)Ti(O TFE)Cl . L-2 (1b) and their Zr(IV) analogues have been shown to mediate eff icient aminoalkyne cyclizations to provide azatitanium intermediates that u ndergo facial C-acylation in the presence of acyl cyanides.