Lidocaine is an integral part of most wetting solutions used in liposuction
. Although the Physician's Desk Reference states that the permissible dose
of lidocaine is 7 mg/kg, doses as high as 75 mg/kg have been used in liposu
ction. Lidocaine is used in the wetting solution even when the procedure is
performed under epidural or general anesthesia. The justification for this
is a reduction in postoperative pain. This study compared the pain between
paired, mirrored sides of 10 patients when lidocaine was used on only one
side. There was no statistically significant difference between the postope
rative pain at 5, 30, 60, and 120 minutes and on the first postoperative da
y. Because there was no difference in pain whether or not lidocaine was use
d, and because Lidocaine is potentially toxic and lethal, this study conclu
des that lidocaine is not necessary in liposuction.