Lymphocytic colitis and sicca syndrome.

Introduction. - Microscopic colitis describes a subset of patients with chr onic watery diarrhea of unknown origin, and normal endoscopic findings and microscopic evidence of an inflammatory infiltrate in the colonic mucosa. W e report two cases associated with sicca syndrome. Exegesis. - A 56-year-old woman and 76-year-old man presented with a histor y of lymphocytic colitis associated with sicca syndrome. Drugs or infectiou s agents were not implicated in the cause of lymphocytic colitis, suggestin g that sicca syndrome may be involved in the pathogenesis of microscopic co litis. Conclusion. - These cases suggest that sicca syndrome should be detected in patients with lymphocytis colitis. (C) 1999 Editions scientifiques et medi cales Elsevier SAS.