Swine veterinary drugs administered via the intra-muscular route. I. Localtolerance when administred in laboratory or breeding conditions.

The study aimed to evaluate muscular damage induced by antibiotics (sulfado xine with thrimetoprime, amoxicillin long acting, lincomycin and oxytetracy cline long acting) administered via the intra-muscular route according to a standardised procedure to pigs in laboratory or farm conditions (2 and 5 m onths old respectively) in order to precise wether laboratory results are c orrelated to farm ones. Post-injection muscle damages were noted and quanti fied according to a morpholopical procedure based on the scoring of macrosc opic observations at injection sites after reglementary withdrawal period o r a longer waiting period. Results showed that lesions are larger and more frequent with farm breeding animals. A great variability of the results sho ws the need to improve the method for the evaluation of such muscle damages .