Paternity probability when a relative of the father is an alleged father

Citation
Jw. Lee et al., Paternity probability when a relative of the father is an alleged father, SCI JUSTICE, 39(4), 1999, pp. 223-230
Citations number
15
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology
Journal title
SCIENCE & JUSTICE
ISSN journal
13550306 → ACNP
Volume
39
Issue
4
Year of publication
1999
Pages
223 - 230
Database
ISI
SICI code
1355-0306(199910/12)39:4<223:PPWARO>2.0.ZU;2-X
Abstract
When scientists use DNA evidence in court, coancestry effects such as popul ation structure and relatedness are usually ignored. In paternity cases, on ly if a particular man has the child's paternal allele at a certain locus, can he not be excluded in the paternity dispute. However, it is certainly t rue that close relatives will be far more likely to have the child's patern al allele than will random members of the reference population. In particul ar, the probability that the true father's brother has the paternal allele is very much greater than that for any other relationship. In this paper, t he authors describe a method for inference in a case where the true father may be a relative of the alleged father. This paper also reports that most current methods overstate the probability that the alleged father is the fa ther.