Preparation and release characteristics of tolmetin sodium matrix tablets with ethylene maleic acid anhydrides

Authors
Baloglu, E Ozer, O Ozyazici, M
Citation
E. Baloglu et al., Preparation and release characteristics of tolmetin sodium matrix tablets with ethylene maleic acid anhydrides, STP PHARM S, 9(4), 1999, pp. 329-334
Citations number
23
Categorie Soggetti
Pharmacology & Toxicology
Journal title
STP PHARMA SCIENCES
ISSN journal
11571489 → ACNP
Volume
9
Issue
4
Year of publication
1999
Pages
329 - 334
Database
ISI
SICI code
1157-1489(199907/08)9:4<329:PARCOT>2.0.ZU;2-E
Abstract
The aim of this study is to prepare the sustained release formulation of to lmetin sodium with different particle sizes containing varying types and pe rcentages of ethylene maleic anhydride resins. The dissolution tests were a pplied and the dissolution kinetics of formulas were obtained. It was seen that the formulations provided sustained release and particle size of drug and the type and the concentration of ethylene maleic anhydride resins affe cted the dissolution rate.