Initial clinical experience at real-time three-dimensional echocardiography in patients with ischemic and idiopathic dilated cardiomyopathy

The geometry of the left ventricle in patients with cardiomyopathy is often sub-optimal for 2-dimensional ultrasound when assessing left ventricular ( LV) function and localized abnormalities such as a ventricular aneurysm. Th e aim of this study was to report the initial experience of real-rime 3-D e chocardiography for evaluating patients with cardiomyopathy. A total of. 34 patients were evaluated with the real-time 3D method in the operating room (n = 15) and in the echocardiographic laboratory (n = 19), Thirteen of 28 patients with cardiomyopathy and 6 other subjects with normal LV function w ere evaluated by both real-time 3-D echocardiography and magnetic resonance imaging (MRI) for obtaining LV volumes and election fractions For comparis on. There were close relations and agreements for LV volumes (r = 0.98, p < 0.0001, mean difference and ejection fractions (r = 0.97, p <0.0001, mean d ifference = 0.001 +/- 0.04) between the real-time 3D method and MRI when 3 cardiomyopathy cases with marked LV dilatation (LV end-diastolic volume >45 0 mi by MRI) were excluded. In these 3 patients, 3D echocardiography signif icantly underestimated the LV volumes due to difficulties with imaging the entire LV in a 60 degrees x 60 degrees pyramidal volume. The new real-time 3D echocardiography is feasible in patients with cardiomyopathy and may pro vide a faster and lower cost alternative to MRI for evaluating cardiac func tion in patients, (C) 1999 by Excerpta Medico, Inc.