Objective: To compare gastrointestinal-related healthcare resource utilizat
ion in arthritis patients with and without dyspepsia.
Study Design: A historical cohort study based on a claims database.
Patients and Methods: Data were obtained from the MarketScan database. Adul
t patients with a diagnosis of arthritis (International Classification of D
iseases, 9th Revision [ICD-9] codes 714.0-715.9) during 1992 and 1993 were
included; individuals with a diagnosis of dyspepsia within the first 3 mont
hs of their arthritis diagnosis were considered study case patients. Each c
ase patient was matched with 4 nondyspeptic arthritis patients based on age
, gender, employment status, and type of insurance plan, Healthcare resourc
e utilization in terms of outpatient services and inpatient admissions duri
ng the first year after the initial arthritis diagnosis was compared betwee
n the case and control groups,
Results: A total of 503 case and 2146 control patients were identified. The
re were no significant differences in demographic characteristics between t
he 2 groups. Dyspeptic patients (cases) had a significantly higher rate of
claims for endoscopic procedures (odds ratio [OR] = 10.0, P<.01) than nondy
speptic patients (controls), Patients with dyspepsia also had a significant
ly higher claim rate of gastrointestinal ulcer or bleeding (OR = 4.2, P<.01
) and were more likely to be hospitalized at least once (OR = 1.4, P<.01),
Dyspeptic patients had overall higher frequencies of use of outpatient serv
ices (53.9 vs 32.5 claims per patient, P<.001) and higher costs for both in
patient admission and outpatient services than nondyspeptic patients.
Conclusion: Dyspeptic arthritis patients have higher healthcare resource ut
ilization and associated costs than nondyspeptic arthritis patients.