Synthesis and antimicrobial activity of some new flavonyl oxime ether derivatives

Authors
Tuncbilek, M Bozdag, O Ayhan-Kilcigil, G Altanlar, N Buyukbingol, E Ertan, R
Citation
M. Tuncbilek et al., Synthesis and antimicrobial activity of some new flavonyl oxime ether derivatives, ARZNEI-FOR, 49(10), 1999, pp. 853-857
Citations number
25
Categorie Soggetti
Pharmacology & Toxicology
Journal title
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
ISSN journal
00044172 → ACNP
Volume
49
Issue
10
Year of publication
1999
Pages
853 - 857
Database
ISI
SICI code
0004-4172(199910)49:10<853:SAAAOS>2.0.ZU;2-K
Abstract
The synthesis of a series of 6 compounds related to 2-(4'-formyl-phenyl)-4H -1-benzopyran-4-one O-substituted oxime and the results of a study of their biological activity are reported. The structural assignments of the compou nds is based upon various spectral data. The prepared compounds were screen ed for their in vitro antibacterial and antifungal activities. Compound F3 exhibited the best antifungal activity compared with ketoconazole and fluco nazole.