Asthma is a common cause of childhood morbidity. The objective of the prese
nt study was to evaluate the factors associated with increased asthma morbi
dity among asthmatic children in Singapore. A cohort of primary school chil
dren (n = 6,404, aged 6-13 years) were evaluated using the American Thoraci
c Society and the Division of Lung Diseases of the National Heart, Lung and
Blood Institute, USA (ATS-DLD) respiratory questionnaire. A total of 2,222
of 6,404 children (34.8%) was found to have reported symptoms of wheezing.
Of these, 899/2,222 (40.5%) reported symptoms of "increased asthma morbidi
ty". This was associated with the younger age group, male sex and higher so
cio-economic status. In addition, concurrent or past allergies were strongl
y associated with increased asthma morbidity, while premature birth and a h
istory of prior childhood respiratory illnesses and infections were predict
ive of greater asthma morbidity. No association was found between increased
morbidity and presence of domestic pets, parental smoking, childcare atten
dance, and the season of birth.