This investigation examined the motivational structure of 170 inpatients di
agnosed with alcoholism according to International Classification of Diseas
es - 10 (F 10.2) and hence also to those of the Diagnostic and Statistical
Manual - IV (303.90) in comparison to 163 demographically very similar pers
ons, both male and female. The proportions in the samples were roughly the
same. Because some of variables of the Motivational Structure Questionnaire
s (MSQ) are distributed to a substantial extent nonnormally, the main analy
ses employ logistic regression analysis of differences between participants
with and without a diagnosis of alcoholism Logistic regression analysis re
vealed significant inter-group differences in the following indices of the
Motivational Structure Questionnaire. The strongest individual predictor fo
r belonging to F 10.2 (DSM-4-303.90) was lower value on Ineffectiveness (R
= -.1500, p = .0004). Lower value in Aversive Motivation showed similarly l
ow lewels (R = -.0682, p = .0417), while with increasing Sorrow in Excess o
f Joy value (R = .0968, p = .0119) the probability to belong to the sample
[ICD-10 (F 10.2) and/or DSM-4 (303.90)] increased. The results suggest grou
p differences both in the effect of treatment, and in the effect of brain r
eward mechanism.