Directed ortho metalation and Suzuki-Miyaura cross-coupling connections: regiospecific synthesis of all isomeric chlorodihydroxybiphenyls for microbial degradation studies of PCBs

Authors
Nerdinger, S Kendall, C Marchhart, R Riebel, P Johnson, MR Yin, CF Eltis, LD Snieckus, V
Citation
S. Nerdinger et al., Directed ortho metalation and Suzuki-Miyaura cross-coupling connections: regiospecific synthesis of all isomeric chlorodihydroxybiphenyls for microbial degradation studies of PCBs, CHEM COMMUN, (22), 1999, pp. 2259-2260
Citations number
15
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
22
Year of publication
1999
Pages
2259 - 2260
Database
ISI
SICI code
1359-7345(1999):22<2259:DOMASC>2.0.ZU;2-8
Abstract
Monochloro DHBs 1a-d and 2a-c have been regioselectively synthesised in goo d overall yields by a combination of directed ortho metalation and Suzuki-M iyaura cross-coupling.