Since the first experiences with direct-to-consumer (DTC) prescription drug
advertising in the early 1980s, pharmaceutical marketers, government regul
ators, researchers, health practitioners, and consumers have been both perp
lexed and intrigued by this practice. As experience with DTC advertising ha
s expanded, so has knowledge and understanding of its risks and rewards. Th
is article discusses important issues in DTC advertising, such as the effec
ts it may have on the patient-practitioner relationship, the diffusion and
adoption of new drugs, prices, and competition. It also discusses the futur
e of DTC advertising.