Contrast optimization for assessment of the colonic wall and lumen in MR colonography

This report focuses on the optimization of magnetic resonance colonography for combined virtual endoluminal and TP-weighted wall analysis of the colon and demonstrates the potential of the single-shot fast spin-echo (SSFSE) s equence for identifying colorectal pathologies, A 45 degrees flip angle in the three-dimensional spoiled gradient-echo sequence and a TE of 60 msec in the SSFSE sequence in conjunction with a 10 mM gadolinium concentration in the enema results in maximal contrast for the delineation of the colonic l umen in T1-weighlted imaging and the colonic wall in TB-weighted imaging. T he SSFSE sequence reveals hyperintense signal for inflammatory disease and most polyps exceeding 10 mm in size. It supplements the virtual endoluminal assessment by aiding in the differentiation between mass lesions and fecal matter or residual air. (C) 1999 Wiley-Liss, Inc.