A 22-year-old Caucasian woman with a 6 year history of persistently active,
systemic onset juvenile rheumatoid arthritis (JRA) developed symptoms of h
eadache, dry cough, nausea, vomiting, abdominal pain, diarrhea, and dehydra
tion associated with a high fever, elevated liver enzymes, and lymphopenia.
Subsequent investigation revealed acute infection with parvovirus B19. Fol
lowing clinical improvement over 10-14 days solely with supportive care, he
r underlying disease remained in remission for about 7 months.