The Cochrane Collaboration is an international organisation that aims to he
lp people make well-informed decisions about health care by preparing, main
taining and ensuring the accessibility of systematic reviews of the benefit
s and risks of health care interventions. We describe the structure and act
ivities of the Cochrane Collaboration, especially focusing on the carrying
out of systematic reviews of randomised trials. We describe the place of su
rgery and surgeons within the Cochrane Collaboration.