Successful liver transplantation from a donor with brodifacoum intoxication

We describe our use of a liver allograft from a donor who died of intracran ial hemorrhage after brodifacoum ingestion. Because brodifacoum can remain in the human body for months, the recipient's posttransplantation coagulati on profiles and serum brodifacoum levels were monitored closely. Her posttr ansplantation course was excellent, with no coagulation problem. At 15 mont hs posttransplantation, she is well, with normal liver function and coagula tion profile. We conclude that brodifacoum toxicity is not a strict contrai ndication to liver donation. Copyright (C) 1999 by the American Association for the Study of Liver Diseases.