Structures of two novel isomeric triterpenoid saponins from Anthocephalus cadamba

Authors
Sahu, NP Koike, K Jia, ZH Achari, B Banerjee, S Nikaido, T
Citation
Np. Sahu et al., Structures of two novel isomeric triterpenoid saponins from Anthocephalus cadamba, MAGN RES CH, 37(11), 1999, pp. 837-842
Citations number
24
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
MAGNETIC RESONANCE IN CHEMISTRY
ISSN journal
07491581 → ACNP
Volume
37
Issue
11
Year of publication
1999
Pages
837 - 842
Database
ISI
SICI code
0749-1581(199911)37:11<837:SOTNIT>2.0.ZU;2-A
Abstract
Two novel triterpenoid saponins, phelasin A (1) and phelasin B (2), were is olated from the bark of Anthocephalus cadamba (Roxb) Mig. The structures we re established by one- and two-dimensional H-1 and C-13 NMR spectroscopy. T he aglycone of 1, phelasingenin (3), is a new compound characterized as 3 b eta-hydroxy-olean-18-ene-27,28-dioic acid. Molecular mechanics and molecula r dynamics studies carried out on 3 showed the preferred conformation adopt ed by the molecule. Copyright (C) 1999 John Wiley & Sons, Ltd.