A criterion for the optimization of the process producing L-Cystine on an industrial scale

Authors
Yamamoto, Y Akashi, K Kobayashi, T Utagawa, T Fujita, I
Citation
Y. Yamamoto et al., A criterion for the optimization of the process producing L-Cystine on an industrial scale, NIP NOG K-J, 73(11), 1999, pp. 1167-1172
Citations number
3
Categorie Soggetti
Agricultural Chemistry
Journal title
NIPPON NOGEIKAGAKU KAISHI-JOURNAL OF THE JAPAN SOCIETY FOR BIOSCIENCE BIOTECHNOLOGY AND AGROCHEMISTRY
ISSN journal
00021407 → ACNP
Volume
73
Issue
11
Year of publication
1999
Pages
1167 - 1172
Database
ISI
SICI code
0002-1407(199911)73:11<1167:ACFTOO>2.0.ZU;2-7
Abstract
L-Cystein (CysH) is produced from DL-2-thiazolin-4-carboxylic acid (ATC) us ing enzymatic activity of Pseudomonas strains, and the oxidized to produce L-cystine (Cys). Criteria for the optimization of the process producing Cys were studied for the scaling up of this process. The oxidation-reduction potential (ORP) was found to be useful to optimize the process. The ORP value of - 450 mV was optimum to produce Cys at the hi ghest yield of 83% (mol yield) from the 75 mg/mL of ATC in a bench plant sc ale reactor.