Treatment of malignant neoplasms of the parotid gland

Citation
M. Magnano et al., Treatment of malignant neoplasms of the parotid gland, OTO H N SUR, 121(5), 1999, pp. 627-632
Citations number
25
Categorie Soggetti
Otolaryngology
Journal title
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
ISSN journal
01945998 → ACNP
Volume
121
Issue
5
Year of publication
1999
Pages
627 - 632
Database
ISI
SICI code
0194-5998(199911)121:5<627:TOMNOT>2.0.ZU;2-R
Abstract
In this study we evaluated the effects of surgical and radiotherapy treatme nt on local control in 126 patients with malignant tumors of the parotid gl and. The most frequently observed malignant tumors were high-grade tumors ( 68%). Surgical treatment was performed in 81 patients (83.5%). Total conser vative parotidectomy was the most frequent procedure (74%), and radiotherap y was performed in 81 patients (83.5%). The global survival rate was approx imately 54% at 5 years, whereas disease-free survival was 47% at 5 years. N o statistically significant difference in survival rate was found between c onservative (52% at 5 years) and radical treatment of the seventh cranial n erve (43% at 5 years). The Incidence of recurrent cancer was 25.7% (25 of 9 7), of which 88% developed during the first 2 years. We report some of the clinical and histologic factors that can influence the prognosis of the dis ease.