Theoretical estimation of the possibility of formation of oxadiazocines inthe nucleophilic addition of resorcinol to pyrimidines and synthesis of new azoloannelated benzooxadiazocines
Ev. Bartashevich et al., Theoretical estimation of the possibility of formation of oxadiazocines inthe nucleophilic addition of resorcinol to pyrimidines and synthesis of new azoloannelated benzooxadiazocines, RUSS CHEM B, 48(8), 1999, pp. 1553-1557
A method was proposed for estimating the possibility of cyclization of addu
cts of resorcinol with pyrimidines to form oxadiazocines based on the confo
rmational criterion and analysis of charges on the C(5) atom of the pyrimid
ine ring and on the H atom of the hydroxy group of the resulting adducts. A
series of new derivatives of 4,5-dihydro-11H-5,11-methanobenzo[g]azolo[1,3
,5]oxadiazocines were synthesized.