In developed countries, through more and more personalized, vaccination in
newborns and young infants is governed by immunization schedules implemente
d by the various states. 'Basic' vaccines must be administered and their ad
ministration can only be systematic with respect to compliance with the imm
unization schedule. To maintain protection in teenagers and adults, the imm
unization schedule recommends systematic booster injections. To provide bet
ter immunization in adults, 'a la carte vaccination' has also been proposed
, i.e., vaccination as a function of need rather than a function of the imm
unization schedule. As acquired immunity may sometimes be rapidly lost, a b
ooster injection may have to be prescribed earlier than the foreseen date.
On the contrary, hyperimmunization with potential complications may be obse
rved if the immunization schedule is followed. As the various specific anti
body titers may be easily assessed using current assay procedures, physicia
ns could thus prescribe, during routine visits, immunoassays according to t
he patient's age and history, and possibly advocate a booster injection. Ei
ther personalizing booster injections in adults, while preserving - and no
doubt improving - immunization in the community, or conforming to a strict
immunization schedule identical from one individual to the other - is the c
hoice that we must consider, beginning today.