Vaccination has become a universal medical intervention. The yearly number
of vaccinations is estimated to be more than one billion. However, vaccinat
ion is still too often poorly administered, representing an inadmissible da
nger, or not done at all, even when the risk justifies its use. Vaccination
is a veritable medical treatment for healthy individuals (mainly children)
, falling within the scope of legal obligation. Above all, it must not run
a risk to the immunized subject. However, actions other than the use of the
product termed 'vaccine' are involved in the vaccination procedure. Though
manufacturing and monitoring of vaccine production are very carefully done
, packaging, shipping and stocking must conform to the prerequisites of qua
lity. Vaccination safety also results from the proper administration of vac
cines. However, post-vaccination surveillance has revealed dangerous practi
ces, notably the use of non-sterile material in the administration of injec
tions. The consequences are sometimes devastating. It is absolutely necessa
ry, therefore, to urgently investigate ways to limit and eliminate this ris
k, and to assure the proper use of vaccines. A further worry is the decisio
n that vaccination will not be introduced when in fact epidemiological cond
itions require it. When a vaccine does exist, the decision to not vaccinate
even when an epidemic is threatening is a public health error, as numerous
are the examples of epidemics of meningitis and yellow fever could have be
en avoided.