During the National Meeting of Clinical Pharmacology (Giens 1998), the work
ing group exchanged information and examined the new therapeutic approaches
to inflammation in asthma. The group performed a state of the art review o
f the current research on mediators of bronchial inflammation to determine
new pharmacological targets of therapeutic interest. An update on the devel
opment of potential drugs acting on these targets was established. Specific
ities related to asthma in terms of evaluation and development of anti-infl
ammatory drugs were discussed. The place of pharmacoeconomy in the developm
ent of anti-asthmatic drugs was specified.