Symposium overview: Alterations in cytokine receptors by xenobiotics

A symposium entitled Alterations in Cytokine Receptors by Xenobiotics was h eld at the 137th Annual Meeting of the Society of Toxicology (SOT) in Seatt le, Washington. The symposium was sponsored by the Immunotoxicology Special ty Section of SOT and was designed to present information on the effect of several different classes of xenobiotics on various aspects of receptor fun ction (i.e., post-receptor signal transduction of receptor expression), or the involvement of cytokine receptors in the action of the toxicant under c onsideration. This symposium brought together scientists in the area of rec eptor immunobiology whose expertise in receptor modulation encompassed thos e major signaling agents involved in the normal immune response, i.e., proi nflammatory, cytokines, chemokines, interleukins, and interferons. The foll owing is a summary of each of the individual presentations.