Autologous blood donation in children has become a standard of care. Childr
en have to live with the life-time complications associated with allogeneic
blood including the transmission of known and unknown pathogens, and the i
mpact of alloimmunization on future blood transfusions, organ transplants a
nd pregnancies. Donor reaction, allogeneic exposure and utilization rates i
n pediatric preoperative autologous donation (PAD) programs are as good if
not better than reported in adult literature. Children are very resilient w
hen undergoing extreme isovolemic hemodilution (IHD). PAD, IHD and intraope
rative blood recovery appear to be useful components of a pediatric blood c
onservation program. Prospective, randomized studies addressing the specifi
c needs of children are required to properly define their perioperative rol
e. (C) 1999 Elsevier Science Ltd. All rights reserved.