5-Amino-4-(4-methoxyphenyl)-2-phenyl-7-(pyrrolidin-1-yl)-1,6-naphthyridine-8-carbonitrile

Citation
R. Sankaranarayanan et al., 5-Amino-4-(4-methoxyphenyl)-2-phenyl-7-(pyrrolidin-1-yl)-1,6-naphthyridine-8-carbonitrile, ACT CRYST C, 55, 1999, pp. 1670-1672
Citations number
13
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
ISSN journal
01082701 → ACNP
Volume
55
Year of publication
1999
Part
10
Pages
1670 - 1672
Database
ISI
SICI code
0108-2701(19991015)55:<1670:5>2.0.ZU;2-J
Abstract
In the crystal of the title compound, C26H23N5O, there are two independent molecules in the asymmetric unit. The naphthyridine moiety in both molecule s is slightly folded. The dihedral angles between the fused pyridine rings in the molecules are 5.7(1) and 8.2(1)degrees, respectively. The pyrrolidin e ring in both molecules adopts a half-chair conformation. The molecular st ructure is stabilized by a C-H ... N-type intramolecular hydrogen bond with in the two molecules in the asymmetric unit and the packing is stabilized b y intermolecular N-H ... O hydrogen bonds.