We examined whether impaired coronary flow reserve in healthy men is associ
ated with changes in cardiac performance and exercise-induced ischemia. A c
omparison between 7 asymptomatic men with low flow reserve (<3.5) and 8 men
with normal flow reserve (>3.5) showed no differences in these parameters,
suggesting that. the mechanisms that control myocardial blood flow during
exercise remain normal despite the alterations in the mechanisms that contr
ol the vasodilatory reaction to dipyridamole.