This paper reports the results of a series of 5 patients who underwent clos
ure of persistent bronchopleural fistula using extrathoracic muscle flaps o
ver a 6-year period. All patients had failed more conservative treatment. T
he surgeries were one- or two-stage procedures performed with the collabora
tion of cardiovascular and reconstructive surgical staffs. There were no as
sociated mortalities. The muscle flaps utilized were the latissimus dorsi,
serratus anterior, pectoralis major, pectoralis minor, and trapezius. The r
esults have been encouraging and allowed the complete closure of the bronch
opleural fistula in the majority of patients. The authors present the best
management of this serious disease, as well as its pathophysiology and clin
ical aspects.