Infection of the expander pocket is the most common complication encountere
d with soft-tissue expansion. It is usually due to direct inoculation with
skin flora either at the time of expander insertion or from extrusion of th
e device. The authors report two cases of infection of tissue expanders in
which the children had concomitant infected sites distant from the prosthes
is. Etiological bacteria of common pediatric infections like otitis media a
nd pharyngitis were cultured from the infected expander pocket, raising sus
picion that translocation of the organism to the expander had occurred. Agg
ressive antibiotic treatment, removal of the prosthesis, and flap advanceme
nt is advocated.