Citation
Ia. Parshikov et al., Biotransformation of N-acetylphenothiazine by fungi, APPL MICR B, 52(4), 1999, pp. 553-557
Citations number
12
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
ISSN journal
01757598
→ ACNP
Volume
52
Issue
4
Year of publication
1999
Pages
553 - 557
Database
ISI
SICI code
0175-7598(199910)52:4<553:BONBF>2.0.ZU;2-R
Abstract
Cultures of the fungi Aspergillus niger, Cunninghamella verticillata, and P
enicillium simplicissimum, grown in a sucrose/peptone medium, transformed N
-acetylphenothiazine to N-acetylphenothiazine sulfoxide (from 13% to 28% of
the total) and phenothiazine sulfoxide (from 5% to 27%). Phenothiazin-3-on
e (4%) and phenothiazine N-glucoside (4%) were also produced by C. verticil
lata, The probable intermediate, phenothiazine, was detected only in cultur
es of P, simplicissimum (6%).