beta-acarbose. VIII - The synthesis of some N-linked carba-oligosaccharides

Authors
Stick, RV Tilbrook, DMG Williams, SJ
Citation
Rv. Stick et al., beta-acarbose. VIII - The synthesis of some N-linked carba-oligosaccharides, AUST J CHEM, 52(9), 1999, pp. 895-904
Citations number
26
Categorie Soggetti
Chemistry
Journal title
AUSTRALIAN JOURNAL OF CHEMISTRY
ISSN journal
00049425 → ACNP
Volume
52
Issue
9
Year of publication
1999
Pages
895 - 904
Database
ISI
SICI code
0004-9425(1999)52:9<895:BV-TSO>2.0.ZU;2-Z
Abstract
Two carbohydrate triflates have been used to alkylate a 1-epivalienamine de rivative to give small amounts of the desired secondary amines, in addition to amounts of the products of elimination. Deprotection of the secondary a mines afforded a carba-disaccharide and a carba-tetrasaccharide which have been shown to be good inhibitors of beta-glucosidases.