Computer analysis of regulatory patterns in completely sequenced bacterialgenomes. Translation initiation of ribosomal protein operons

Signals of translation initiation of operons of Haemophilus influenzae ribo somal proteins were predicted. This process is regulated by the formation o f secondary;RNA structures to which one of the proteins encoded in a partic ular operon binds. In some cases, these structures imitate the region of pr otein binding to rRNA. Predictions are made by comparing with homologous op erons of Escherichia coli and analogous regions of rRNA and by estimating t he energy of secondary structure formation, It is shown that this regulator y mechanism occurs: in operons L11, S10, S15, spc, and alpha of H. influenz ae and, probably, in operon S15 of Helicobacter pylori, Bacillus subtilis; and Mycoplasma genitalium.