Statistical analysis and prediction of prokaryote ribosomal binding sites

An algorithm for recognition of prokaryotic ribosomal binding sites is sugg ested. The parameter library contains weight matrices for mapping of gene s tarts in various bacterial genomes. Comparison of. the ribosome binding sta rts in different taxonomic groups demonstrates that the signals in Gram-pos itive bacteria are stronger than in Gram-negative bacteria, and in particul ar, Enterobacteria. The recognition matrices are available by e-mail misha@ imb.imb.ac.ru.