Adiabatic solution of Ohmic cable equation: General theory and applicationfor a homogeneous cylindrical cable

Citation
A. Alaburda et al., Adiabatic solution of Ohmic cable equation: General theory and applicationfor a homogeneous cylindrical cable, BIOFIZIKA, 44(4), 1999, pp. 714-719
Citations number
6
Categorie Soggetti
Biochemistry & Biophysics
Journal title
BIOFIZIKA
ISSN journal
00063029 → ACNP
Volume
44
Issue
4
Year of publication
1999
Pages
714 - 719
Database
ISI
SICI code
0006-3029(199907/08)44:4<714:ASOOCE>2.0.ZU;2-6
Abstract
An adiabatic solution of the Ohmic cable equation is suggested, which reduc es the non-stationary equation to a stationary form.-The adiabatic length c onstant of the stationary equation is time-dependent. The adiabatic solutio ns for the boundary conditions that change in time linearly and exponential ly were studied. In the latter case, the adiabatic length constant does not depend on time though it differs from the usual length constant.:The cable input characteristics of exact and adiabatic solutions were compared in th e cases of the voltage- and current-clamp, and electric field stimulation. The adiabatic and exact solutions are identical for the rising exponential stimuli. For the falling exponential stimuli, the adiabatic solution determ ines the exact asymptotic solution if the stimulus decays slower than the r elaxation of initial conditions. It is propose to use linear and exponentia l ramp stimulation in electrotonic measurements.