Detection of DNA damage and identification of UV-induced photoproducts using the CometAssay (TM) kit

We introduce the first commercially available comet assay for the detection and quantification of DNA damage in individual eukaryotic cells. The major difficulty Of the comet assay is the preparation of the slides needed to i mmobilize the samples throughout the lysis and electrophoretic procedure. T he CometAssay(TM) kit uses a proprietary technology to precoat glass micros cope slides to allow direct application of the agarose embedded sample with out any additional slide treatment. in this report, Mle discuss the detecti on of DNA damage in individual cells exposed to ultraviolet irradiation usi ng the new CometSlides(TM) and their cost compared to traditional slides.