Ropivacaine and bupivacaine for long-term epidural infusion in a small child

Ropivacaine is assumed to be less toxic than bupivacaine but there are no r eports concerning its long-term use in paediatric anaesthesia. We report th e use of ropivacaine for long-term epidural anaesthesia in a 21-month-old g irl. In two consecutive periods of 3 days each, 0.5% bupivacaine and 0.5% o r 0.75% ropivacaine were administered to facilitate painful vaginal brachyt herapy. The mean dose of bupivacaine increased from 1.05 to 1.32 mg kg(-1) h(-1) and that of ropivacaine increased from 1.40 to 3.86 mg kg(-1) h(-1). No toxic side effects were observed. We conclude that both epidural ropivac aine and bupivacaine were effective and safe during long-term epidural anae sthesia in this particular case. However, the doses were potentially toxic and should therefore be used with extreme caution.