Most wireless phones and their corresponding base stations operate at a ver
y low power output and in the radiofrequency Range of 800 to 2000 Megahertz
. Current international guidelines protect against thermal biological effec
ts in terms of the local or whole-body specific absorption rate (SAR). Pote
ntial non-thermal bio-effects resulting; from the use of wireless phones ar
e not established and laboratory (i.e., in vitro, in vivo) studies have sho
wn conflicting results. Epidemiological studies of potential human health e
ffects are few but are expected to emerge in the near future. Challenges to
epidemiological research include difficult exposure assessment, selection
of appropriate controls, potential confounding bias, and validation of outc
ome. Scientists, community advocacy groups, and public health professionals
must be equipped to critically analyze the emerging evidence within a bene
fit/risk assessment framework.